ResearchScience

Researchers Identify New Protein Recycling Pathway in Cellular Waste Management

A groundbreaking study has uncovered a previously unknown cellular recycling pathway that uses optineurin as an adaptor protein. This discovery reveals how cells selectively degrade proteins from the Golgi apparatus using specialized ubiquitin chains.

New Cellular Recycling Pathway Discovered

Researchers have identified a previously unknown mechanism for protein degradation within cells, according to a recent scientific report. The study reveals that optineurin functions as an adaptor protein in Golgi membrane-associated degradation (GOMED), providing new insights into how cells manage protein waste. This discovery represents what sources indicate is the third known mechanism of ubiquitin-mediated proteolysis, alongside the well-established proteasome and autophagy pathways.

Science

Cascadia Megathrust Quakes Could Potentially Trigger San Andreas Fault Ruptures, Geological Evidence Suggests

Geological researchers have uncovered compelling evidence that major earthquakes along the Cascadia subduction zone may trigger subsequent ruptures along California’s San Andreas Fault. The findings, based on analysis of sediment cores spanning three millennia, suggest these two major fault systems may be more interconnected than previously understood. Scientists indicate this discovery has significant implications for earthquake preparedness along the entire Pacific coast.

Interconnected Fault Systems Revealed Through Sediment Analysis

According to reports from researchers at Oregon State University, a newly discovered geological connection suggests that a major earthquake along the Cascadia subduction zone could potentially trigger significant seismic activity along California’s San Andreas Fault. The research team, led by paleoseismologist Chris Goldfinger, analyzed 137 different sediment cores collected from both geological zones over five research voyages, uncovering evidence of synchronized earthquakes dating back approximately 3,000 years.